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Gang WANG, MD, PhD           xjwgang@fmmu.edu.cn 
Academic title: Professor, PhD supervisor, Chief physician
Administrative title: Departmental Chairman of Dermatology
Research interest: Psoriasis, Blistering skin diseases, Dermatopathology
   
   
Educational background:
  • MD, Fourth Military Medical University, 1990~1993
  • PhD, Fourth Military Medical University, 1997~2000
  • Visiting scholar, University of Hokkaido, 2005~2007
Professional highlights:
  • Member of standing committee, China Dermatologist Association
  • Vice-chairman, Committee of Psoriasis, China Society of Dermatology
  • Member, European Academy of Dermatology and Venereology
  • Youth Member, Chinese Society of Dermatology
  • Invited Reviewer, Chinese Medical Journal (CMJ English edition)
  • Editorial Board Member, Eur J Dermatol
  • Visiting professor, Thomas Jefferson University
  • Visiting professor, Department of Dermatology, Hokkaido University
Selected publications:
  • Jin L, Wang G. Keratin 17: A Critical Player in the Pathogenesis of Psoriasis. Med Res Rev. 2013 May 30. doi: 10.1002/med.21291. [Epub ahead of print] PubMed PMID: 23722817.
  • Wang L, Gao T, Wang G. Solitary angiokeratoma on palms and soles: A clinicopathological analysis of 21 cases. J Dermatol. 2013 Jun 5. doi: 10.1111/1346-8138.12192.
  • Wang L, Gao T, Wang G. Acral hemosideric lymphatic malformation. J Cutan Pathol. 2013 Mar 6. doi: 10.1111/cup.12143.
  • Wang L, Wang G, Gao T. Congenital melanocytic nevus with features of hybrid schwannoma/perineurioma. J Cutan Pathol. 2013 Mar 11. doi: 10.1111/cup.12076.
  • Wang L, Liu L, Wang G, Gao T. Congenital disseminated tufted angioma. J Cutan Pathol, 2013, 40(4):405-408.
  • Wei C, Jian Z, Wang L, Qiang H, Shi Q, Guo S, Li K, Huang Y, Liu L, Li Q, Luan Q, Yi X, Li X, Wang G, Gao T, Li C. Genetic variants of the APE1 gene and the risk of vitiligo in a Chinese population: A genotype-phenotype correlation study. Free Radic Biol Med, 2013, 58C: 64-72.
  • Song P, Wang XW, Li HX, Li K, Liu L, Wei C, Jian Z, Yi XL, Li Q, Wang G, Li CY, Gao TW. Association between FOXP3 polymorphisms and vitiligo in a Han Chinese population. Br J Dermatol, 2013 Apr 12. doi: 10.1111/bjd.12377
  • Fu M, Li W, Tian R, Gao J, Xing Y, Li C, Wang G, Li C, Gao T, Han H, Liu Y.Innate autoreactive B cells as antigen-presenting cells in the induction of tolerance to conserved keratin polypeptide. Cell Immunol, 2013, 281(1): 76-84.
  • Qiao H, Abe R, Saito N, Fujita Y, Hayashi-Ujiie I, Wang G, Haga S, Wu C, Ohmiya Y, Ozaki M, Shimizu H. A Method for Intravital Monitoring of Human Cells Using a Far-Red Luminescent Probe in Graft-Versus-Host Disease Model Mice. J Invest Dermatol, 2013 ,133(6): 1692.
  • He Z, Jin L, Liu ZF, Hu L, Dang EL, Feng ZZ, Li QJ, Wang G. Elevated serum levels of interleukin 21 are associated with disease severity in psoriasis patients. Br J Dermatol, 2012, doi: 10.1111/j.1365-2133. 2012.10899.x. PMID: 22356196.
  • Zhang W, Dang E, Shi X, Jin L, Feng Z, Hu L, Wu Y, Wang G . The pro-Inflammatory cytokine IL-22 up-regulates keratin 17 expression in keratinocytes via STAT3 and ERK1/2. PLoS ONE, 2012, 7: e40797.
  • Li K, Shi Q, Yang L, Li X, Liu L, Wang L, Li Q, Wang G, Li CY, Gao TW. The association of vitamin D receptor gene polymorphisms and serum 25-hydroxyvitamin D levels with generalized vitiligo. Br J Dermatol, 2012 Jul 4. doi: 10.1111/j.1365-2133.2012.11132.x.
  • Fu M, Wang G. Keratin 17 as a therapeutic target for the treatment of psoriasis. J Dermatol Sci, 2012, 67:161-5.
  • Shi X, Jin L, Dang E, Chang T, Feng Z, Liu Y, Wang G. IL-17A upregulates keratin 17 expression in keratinocytes through STAT1- and STAT3-dependent mechanisms. J Invest Dermatol, 2011, 131: 2401-2408.
  • Wang L, Wang G, Wang L, Gao T. Myxoid intravascular fasciitis. J Cutan Pathol, 2011, 38: 63-66.
  • Li Q, Lv Y, Li C, Yi X, Long HA, Qiao H, Lu T, Luan Q, Li K, Wang X, Wang G, Gao T. Vitiligo autoantigen VIT75 is identified as lamin A in vitiligo by serological proteome analysis based on mass spectrometry. J Invest Dermatol, 2011, 131: 727-734.
  • Chang T, Sun L, Wang Y, Wang D, Li W, Li C, Gao T, Liu Y, Wang G. Inhibition of keratin 17 expression with antisense and RNAi strategies: exploring novel therapy for psoriasis. Exp Dermatol, 2011, 20, 555-560.
  • Luan Q, Sun J, Li C, Zhang G, Lv Y, Wang G, Li C, Ma C, Gao T. Mutual enhancement between heparanase and vascular endothelial growth factor: a novel mechanism for melanoma progression. Cancer Lett, 2011, 308: 100-111.
  • Wang G, Ujiie H, Shibaki A, Nishie W, Tateishi Y, Kikuchi K, Li Q, McMillan JR, Morioka H, Sawamura D, Nakamura H, Shimizu H. Blockade of autoantibody-initiated tissue damage by using recombinant Fab antibody fragments against pathogenic autoantigen. Am J Pathol,2010, 176: 914-925.
  • Liu L, Li C, Gao J, Li K, Zhang R, Wang G, Li C, Gao T. Promoter variant in the catalase gene is associated with vitiligo in Chinese people. J Invest Dermatol, 2010, 130: 2647-53.
  • Wang L, Wang G, Fan P, Gao T. Linear arrangement of hypopigmented Spitz nevi on the ear after trauma. J Dermatol, 2010, 37:346-349.
  • Ujiie H, Shibaki A, Nishie W, Sawamura D, Wang G, Tateishi Y, Li Q, Moriuchi R, Qiao H, Nakamura H, Akiyama M, Shimizu H. A Novel Active Mouse Model for Bullous Pemphigoid Targeting Humanized Pathogenic Antigen. J Immunol, 2010, 184: 2166-2174.
  • Li Q, Ujiie H, Shibaki A, Wang G, Moriuchi R, Qiao HJ, Morioka H, Shinkuma S, Natsuga K, Long HA, Nishie W, Shimizu H. Human IgG1 Monoclonal Antibody against Human Collagen 17 Noncollagenous 16A Domain Induces Blisters via Complement Activation in Experimental Bullous Pemphigoid Model. J Immunol, 2010, 185: 7746-7755.
  • Wang G, Li C, Gao T. Blepharochalasis: A Rare Condition Misdiagnosed as Recurrent Angioedema. Arch Dermatol, 2009, 145: 498-499.
  • Qiao H, Shibaki A, Long HA, Wang G, Li Q, Nishie W, Abe R, Akiyama M, Shimizu H, McMillan JR. Collagen XVII Participates in Keratinocyte Adhesion to Collagen IV, and in p38MAPK-Dependent Migration and Cell Signaling. J Invest Dermatol, 2009, 129: 2288-2295.
  • Li M, Gao Y, Li C, Liu L, Li K, Gao L, Wang G, Zhang Z, Gao T. Association of COX2 functional polymorphisms and the risk of vitiligo in Chinese populations. J Dermatol Sci, 2009, 53:176-181.
  • Wang L, Wang G, Yang L, Gao T. Multiple clear cell trichoblastoma. J Cutan Pathol, 2009, 36: 370-373.
  • Xing Y, Li W, Lin Y, Fu M, Li CX, Zhang P, Liang L, Wang G, Gao TW, Han H, Liu YF. The influence of BCR density on the differentiation of natural poly-reactive B cells begins at an early stage of B cell development. Mol Immunol, 2009, 46:1120-1128.
  • Fan J, Shen Z, Wang G, Yang H, Liu Y. Secretory expression of human ScFv against keratin in Pichia pastoris and its effects on cultured keratinocytes. Arch Dermatol Res, 2009, 301:367-372.
  • Chen L, Shen Z, Wang G, Fan P, Liu Y. Dynamic frequency of CD4(+)CD25(+)Foxp3(+) Treg cells in Psoriasis vulgaris. J Dermatol Sci, 2008, 51:200-203.
  • Wang L, Yang L, Wang G, Gao T.Granular parakeratosis of eccrine ostia. Am J Dermatopathol, 2008, 30:65-66.
  • Li C, Wang G, Gao Y, Liu L, Gao T. TNF-alpha Gene Promoter -238G>A and -308G>A Polymorphisms Alter Risk of Psoriasis Vulgaris: A Meta-Analysis. J Invest Dermatol, 2007, 127:1886-92.
  • Fu M, Fan PS, Li W, Li CX, Xing Y, An JG, Wang G, Fan XL, Gao TW, Liu YF, Ikeda S. Identification of poly-reactive natural IgM antibody that recognizes late apoptotic cells and promotes phagocytosis of the cells. Apoptosis, 2007, 12: 355-362.
  • Shen Z, Chen L, Liu YF, Gao TW, Wang G, Fan XL, Fan JY, Fan PS, Li CY, Liu B, Dang YP, Li CX. Altered keratin 17 peptide ligands inhibit in vitro proliferation of keratinocytes and T cells isolated from patients with psoriasis. J Am Acad Dermatol, 2006, 54: 992-1002.
  • Wang G, Li CY, Gao TW, Liu YF. Clinical analysis of 48 cases of inverse psoriasis: a hospital-based study. Eur J Dermatol, 2005, 15: 176-178.
  • Wang G, Li CY, Gao TW, Liu YF. Dyschromatosis universalis hereditaria: two cases from a family. Clin Exp Dermatol, 2005, 30: 494-496.
  • Wang G, Liu YF, Li CY, Lu N, Gao TW, Hua B, Wang Y. Cloning and characterization of antikeratin human antibodies using a semisynthetic phage antibody library. Arch Dermatol Res, 2004, 296:270-277.
  • Wang G, Li C, Gao T. Verrucous haemangioma. Int J Dermatol, 2004, 43: 745-746.
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